Woman lived a life without pain due to genetic changes

Scientists are always extremely interested in peoplewhich are different from the rest. For example, recently they were interested in a woman from Scotland, who throughout her life did not feel pain and considered this to be normal. Up to sixty years, she broke bones, suffered severe burns and underwent serious operations without anesthesia. Upon learning of this, professors from the London Institute of Biomedical Research decided to find out why a woman had such an anomaly - after all, knowing this, they can create an effective cure for chronic pain in other people.

A woman named Joe Cameron shared withinvestigators that she had previously been diagnosed with arthritis in the thigh, but she never felt pain in the joints. Moreover, earlier she could learn that she had burned, only from the traces of charred skin and smell. Her taste was even weakened - a woman could eat red pepper and feel only a "pleasant burning sensation" in her mouth. She also rarely felt anxiety, depression, fear and panic, even during the time of a car accident that happened once.

Upon learning of this, the scientists sequencedthe genome of her, mother and children. The study showed that the cause of its low sensitivity is the Faah gene mutation, which is responsible for physical sensations. The analgesic properties of this gene are provoked by a particle of Faah-Out, which was previously considered to be a "junk" gene.

Scientists intend to study this part more carefully.genome, because ultimately they can help people get rid of chronic pain with the help of genetic engineering. Perhaps they should have done this earlier, as previous studies have already proven that changes in the Faah gene make people calmer and less susceptible to pain.

Remarkably, this is not the only site.genome that affects sensitivity. For example, in Italy there lives a woman named Leticia Marsilla, who, like the other five members of her family, does not feel pain. The study showed that in their case, a mutation in the ZFHX2 gene is responsible for a painless life.

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