General, Research, Technology

Will a magnet help in the fight against sepsis?

Sepsis is one of the most seriousinfectious complications, in which the infectious agent spreads through the human circulatory system, infecting it. With sepsis, people are usually shown antibiotic therapy prescribed for a long time and in extremely high doses. In addition, pathogens are often resistant to therapy, and the human immune system can no longer cope with such a strong infection. But recently, a group of scientists managed to develop a method of magnetotherapy, in which the magnet will remove microorganisms from the blood that are pre-connected with iron-containing antibodies.

It’s worth noting right away that this is not the firstsimilar development and such methods existed before. But they had one important limitation: only one type of antibody could bind to one type of bacterium, therefore, it was necessary to first conduct a blood test, and then “mix” the serum. In addition, such therapy remained ineffective when more than one microorganism caused the septic lesion of the blood.

Now a large group of scientists from the SwissThe Federal Laboratory for Technology and Materials Science, the Adolf Merck Institute, and Harvard University have been able to develop magnetic antibodies that can attach to most existing microorganisms. The principle of action of such a medicine is very simple: the antibody itself is a "needle", one pole of which is "stuck" into the bacterium, and the other is attracted to the magnet. Cleansing occurs approximately like a normal hemodialysis procedure: blood is passed through an apparatus with a powerful magnet that traps bacteria.

Unfortunately, it’s too early to apply technology inwide practice. Currently, specialists are aimed at completing the phase of animal testing. But now it’s already known that iron-containing antibodies, even if they are not excreted from the body during the “blood purification” procedure, then break down within 5 days.