General, Research, Technology

What time of day does memory work best?

Have you ever had such a thing during a conversation withsuddenly you couldn’t remember a person’s phone number or, even worse, his name? And this despite the fact that you clearly remembered all the necessary information and after a time when the need has already passed, did you recall it magically? For a long time there was no scientific explanation for this unusual phenomenon, but recently Japanese scientists revealed this secret in collaboration with their colleagues from Canada. During a laboratory experiment, they found in mice a gene that enhances or weakens the memory of animals at different times of the day. Perhaps this is where our forgetfulness lies.

The efficiency of human memory depends on the time of day

The results of the experiment werepublished in the scientific publication Discover Excellence. At the very beginning, the researchers suspected that temporary memory problems could be caused by a lack of protein called BMAL1, which is produced in the brain called the hippocampus. He is responsible for the work of many processes in our body and accumulates in our body during the day. That is, after waking up from sleep, we have very little of it, but by evening, the concentration of BMAL1 protein increases significantly. In theory, it turns out that the memory of living beings, including humans, does not work well in the morning and reaches its peak in the evening. But is it really so?

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To test the assumption, Japanese andCanadian scientists conducted a laboratory experiment with adult mice. At the first stage of the experiment, the researchers gave the mice a thorough study of a completely new subject. In the second stage, which began a little later, scientists monitored how much time the animals spend next to an already familiar object. As expected, they did not stay close to him for long, because they well remembered all its properties.

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The most interesting part of the experiment has begunafter 24 hours. The mice were divided into two groups: the organisms of individuals from the first sample were not susceptible to changes, but the production of BMAL1 protein was blocked by other mice. Researchers expected that after waking up, both groups of mice would spend much more time with the previously studied subject, because they could not recall its properties due to the lack and complete absence of BMAL1 protein. And the scientists were absolutely right - both groups of mice roamed around the subject for a long time and tried to remember what it was.

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After the experiment, scientists concluded thatanimals and people really have memory problems in the morning. It is likely that it is precisely due to lack of BMAL1 protein that we can’t even remember the phone numbers and names of even close people.

If you had moments when you forgot numbersphones and names of people - maybe you remember what time of day this most often happened? You can share your answer in the comments or in our Telegram chat, it's really very interesting!

According to researchers, their discovery mayto develop new treatments for people with memory impairment. They may even be able to create a cure for dementia, which, according to the World Health Organization, affects about 50 million people worldwide.