General, Research, Technology

The presence of a new DNA structure in human cells has been confirmed.

Perhaps almost any person at least a littlefamiliar with science to the question "what does DNA look like?" will answer "in the form of two spirals." And this statement until the last moment was a fact, an axiom that does not require proof. Recently, however, a group of researchers from Australia discovered a completely new form of DNA structure. And, performing all the same functions, it does not at all resemble the usual two-helix molecule.

Behind the discovery is a group of researchers fromHarvan Institute for Medical Research, led by Professor Daniel Christos. The authors themselves describe the new form as a “twisted knot”, which confirms the long-held hypothesis that our genetic code has a much more complex structure than symmetrically arranged spirals.

“When most of us think about DNA, we thinkabout the double helix. Our new study reminds us that there are completely different DNA structures. And this may well be extremely important for the work of our cells. It is important to note that the forms of different molecular variants influence the way our entire biology functions. ”


I-motif sketchy

The DNA fragment is called i-motif. In laboratory conditions, it was observed earlier, back in the 1990s, but was first found in the cells of some animals in the middle of this year. Continuing the research, a team of scientists recently found out that i-motif is also present in functioning human cells.

"I-motif is a four-chain" twisted knot "DNA It is formed as follows: on the same DNA strand, the nitrogenous base of cytosine binds to each other. This is fundamentally different from what we are used to seeing, because cytosine is usually associated with guanine according to the principle of complementarity, ”explained genome researcher Marcel Dinger.

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