About the fact that you can get a lot by the eyesinformation about a person has been known for a long time. For example, doctors can determine some neurological diseases, hearing acuity. Psychologists have even learned to identify some of the personality characteristics of a person. But, as it turned out, this is not all that the eyes can tell. A recent study by Chinese scientists showed that the retina of the eye can reveal the true biological age of a person. To be more precise, microvessels that are contained inside the eye speak of biological age. Using them, it is easy to identify the difference between chronological and biological age. The risk of imminent death of a person depends on this difference in age.
The risk of early death is associated with a person's biological age.
The risk of death usually increases naturallywith increasing chronological age. However, it varies greatly among people of the same age. The reason lies in the biological age, which can be different, since it is influenced not only by time, but also by many other factors. Not so long ago, we said that even regular lack of sleep leads to an increase in biological age. Given that this indicator is individual, modern medicine needs a reliable mechanism that will allow it to be determined with a sufficiently high accuracy.
For this purpose, scientists have studied a variety ofpossible biomarkers such as genes, blood pressure, cognitive abilities, immune function, etc. In the course of research earlier, scientists have found that light-sensitive nerve tissue in the eyeball can be an indicator of biological age. The latest study by Chinese scientists, which was published in the British Journal of Ophthalmology, confirmed that the retina is
“The retina is a unique “window”through which it is possible to assess the pathological processes of systemic vascular and neurological diseases associated with the risk of death,” the authors of the new work report.
Artificial intelligence has learned to determine the biological age
Scientists turn to artificial intelligenceto calculate a person's biological age based on retinal analysis. In order for the system to determine age deviations, the authors of the work used machine learning technologies. As a result, she analyzed 80,000 fundus images taken from more than 40,000 people aged 40 to 69.
To find out how accurately the system has learnedto determine the biological age, she was given to analyze 19 thousand images of the fundus of the experiment participants, who had relatively good health. Scientists suggest that in people with good health, biological age is close to chronological. As a result, the assumption was confirmed - the system showed a fairly high accuracy. The discrepancy between biological and chronological age was up to 3.5 years.
Then they analyzed the images of the fundusmore than 30 thousand people gathered over the past 11 years. The state of health of these people was not known to doctors. Artificial intelligence showed that in 4.5% of people the difference between chronological and biological age was more than ten years. In 28% of participants, the age difference was more than 5 years. In 51% of people, this was more than 3 years. In fact, most people's eyes were older than their actual age.
Risk of early death depends on biological age
Further research has shown that increasedBiological age increases the risk of death from causes other than cardiovascular disease and cancer by 49-67%. With each year of age difference, the risk of mortality increases by 2% for any cause and by 3% for causes not related to cancer and cardiovascular disease.
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Interestingly, the authors of the work did not findrelationship between the state of the retina and mortality from cardiovascular diseases. In addition, the study was observational in nature, so scientists could not establish a causal relationship. But the work showed the most important thing - the retina can be an important biomarker that determines aging.