Not only is the transplantation of donor organsis an extremely complex process, so in medicine there is also a shortage of them. The fact is that most of them are quickly damaged and become unsuitable for transplantation, and the lungs are considered a particularly vulnerable organ. Fortunately, researchers from the Columbia School of Engineering and Vanderbilt University have developed an effective way to restore the lungs within 36 hours. The method was tested on pig lungs, and should be effective in the case of human organs.
Statistics states that 80% of donor lungs ineventually become too damaged for implantation. Most often, the damage occurs due to the ingestion of gastric contents into the respiratory tract, where it begins to dissolve the tissues important for lung function.
To prevent the destruction of tissues and savelung vitality, the researchers used the method of cross-circulation. In particular, they connected the donor lungs to the recipient animal so that its blood would flow through the damaged tissues and restore them. Using this technology, the researchers kept the lungs alive for 36 hours.
During this time, the cells began to recover, andlung work has improved markedly. By the end of the experiment, the lungs met all the quality criteria that are currently required for transplantation. Before applying the technology in real conditions, researchers will have to evaluate the durability of the reconstructed lungs, as well as their response to the drugs prescribed after transplantation.
A similar experiment in mid-April conductedResearchers at Duke University - they literally "resurrected" the pig's brain four hours after its death. More details about this achievement of scientists can be read in our material.
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