Despite the second year of the pandemic and deployed duringmany countries around the world are vaccinated, the question of how long immunity will last after vaccination is still unanswered. The main reason is probably the novelty of the SARS-CoV-2 virus that causes COVID-19. To date, even the closest relatives of the new coronavirus SARS and MERS have not been fully studied, although more than 15 years have passed since their appearance, and new strains of influenza appear every year. But in a pandemic, all means are good and countries have started vaccination without an answer to the question of whether it is necessary to re-vaccinate and, if so, when? Recently, vaccine manufacturers Pfizer announced that nine months after the second vaccination (the vaccine is delivered in two stages, like the Russian Sputnik), a third dose of the vaccine will be required. This is necessary to increase protection against coronavirus. Research by BioNTech and Pfizer shows that after six months, protection is no longer 95%, but 91%; they also have data indicating that the presence of antibodies in the body is lower after eight months.
Immunity after vaccination
At the time of this writing in the worldMore than five COVID-19 vaccines have been developed with proven efficacy in large-scale studies. But the most important question remains - how long will the vaccine immunity last and will it not be necessary to get vaccinated every year, as for example, with the flu? It is difficult to answer this question, also because, judging by the experience of fighting other infectious diseases, it is impossible to predict the duration of immunity (for example, by the level of antibodies) - for different diseases the situation develops in different ways and different components of the immune system are important.
But even in the case of the new coronavirus infectionsomething is already becoming clear today: most likely, everything will be all right with the acquired vaccine immunity. The real problem is the new strains of COVID-19 that are spreading around the planet despite the measures taken to combat the infection. So, experts from the World Health Organization (WHO) are carefully studying the situation with the spread of a new strain of SARS-CoV-2 in India, which is rumored to be very infectious and has already learned to deceive the body's defense system.
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Immunity after vaccination - "Sputnik-V"
According to RBC, on April 10, the head of the Center.Gamalei (the manufacturer of the Sputnik-V vaccine) expressed the hope that "the vaccine will work for five years or longer, possibly indefinitely." Earlier, Alexander Gintsburg estimated the duration of antibodies in the body after vaccination at two years.
“I have a hope that the vaccine will beto act not for a year or two, but for life. I injected myself twice, well, live there for 5-10 years, longer. As I say, I will leave my antibodies in my will to my descendants, ”Gunzburg said.
At the same time, at the Center. The Gamaleys note that those whose antibody levels have decreased after vaccination will be re-vaccinated as part of scientific research. Generally experts estimate the duration of Sputnik's operation at two years; hope for a longer one, includingthe indefinite period of validity of the vaccine is preserved. Let me remind you that recently my colleague from Appleinsider took a fancy to "Sputnik" and shared his experience in this article.
Immunity after vaccination - Pfizer
Based on clinical trials with 40000 participants, the vaccine produced by BioNTech and Pfizer provides protection against COVID-19 in 95% of cases. In real terms, as El Pais writes with reference to Israel, where more than five million people have already been vaccinated, this percentage is even higher - 96 or 97%.
However, company research shows that six months after vaccination, protection is no longer 95%, but 91%. Moreover, they also have data indicating that eight months after vaccination, the presence of antibodies in the body is lower... Thus, to increase immunity and achieve 100% effectiveness, a third dose of the vaccine will be needed.
Interesting: Deaths from the Pfizer vaccine have been reported. What's happening?
According to Spanish El Pais, CEOPfizer, the American partner of the German company BioNTech, said in an interview two weeks ago that the third dose of the vaccine is likely needed somewhere between six and 12 months after the second injection. I also note that Pfizer vaccinations will most likely be carried out annually - again, due to the problem of new strains emerging.