The eyes are among the most unreliable andeasily injured human organs, prone to numerous diseases and experiencing constant stress. Meanwhile, the loss of vision deprives a person of the possibility of a full life, restricts his mobility. Scientists all over the world are actively working on a technology to restore damaged retina. Wildlife research has shown that some species of fish, in particular small zebrafish, have the unique property of retinal regeneration.
The study of the genome of the fish showed that it is twoa third matches the human genome. This similarity allowed scientists to wonder about the possibility of transferring the ability to restore vision into human genes. These genes are found in zebrafish. The retina of the eye is a complex structure of photoreceptors, neurons and synapses designed to read a light image, convert them into nerve impulses that are transmitted to the brain.
In addition to zebrafish, some other fish and reptiles also have the ability to regenerate the retina. For the restoration of vision, they are responsible for Müller cells, which are capable of transforming into retinal neurons.
During the study, the response of zebrafish, mice andchickens, for damage to the retina, at the American University of Hopkins, it was revealed the presence of special genes that block trauma. The immune cells began to protect and cleanse the damaged areas. By manipulating the conversion of Müller cells into retinal cells in mice, the researchers were able to begin the process of repairing visual neurons.
The study authors believe that theThe results indicate the potential for regeneration not only in reptiles and fish, but also in mammals, which include humans. Currently, the study of the possibility of restoring vision in animals and humans is at an initial stage, and it is too early to talk about the imminent creation of a practical scheme for vision regeneration.