Each of us has been bitten at least once in their lives.small but extremely unpleasant creatures - ticks. Being carriers of bacteria of the genus Borrelia, which, despite their noble name, are able to infect the human nervous system, his heart, skin and joints, ticks infect more than 300,000 people on the planet every year. Be that as it may, humanity will soon be one less problem: scientists have created a unique drug that can cope even with the most resistant strains of pathogens Borreliosis or Lyme disease (these diseases are transmitted throughtick bite). The new drug, based on the antibiotic azlocillin, helps in treating not only the underlying disease, but also a number of other infections, reports nature.com. How does an antibiotic manage to defeat a disease for which there was no cure before?
Can Borreliosis Be Cured?
We often associate the spring period withpicnics in the open air, long walks in nature and other outdoor activities. The main danger at this pleasant time is ticks - potential carriers of some dangerous diseases, the main of which is borreliosis or Lyme disease. Although for a long time there was no vaccine for this disease, the disease could be defeated in the early stages with antibiotics, but even if they were used, up to 20% of all patients were forced to suffer from severe symptoms of borreliosis for almost their entire lives. So, starting with a simple reddening of the skin at the site of the bite, the disease gradually progresses as the spots expand. Some time after infection, the patient develops the main symptoms of Lyme disease, which are manifested in loss of sensation and motor activity, as well as in visual impairment and even serous meningitis.
Although what exactly causes the long coursethe disease is still not known for certain, scientists believe that all the fault is resistant to the usual drugs strains of the pathogen. Wanting to confirm or refute this theory, researchers from Stanford University decided to test more than 8,000 different chemical compounds, 50 of which were subsequently selected to create a vaccine not only for the treatment of Lyme disease, but also other dangerous infections. One of the selected substances turned out to be the so-called azlocillin, which is most often used to treat peritonitis, pneumonia, kidney and urinary tract infections.
You can find even more useful articles about medicine and related sciences in our channels in Yandex.Zen and Telegram.
To test antibiotic properties, authorsthe studies tested azlocillin in mice, and the result of the experiment showed that the common antibiotic really helps to cope with the symptoms of borreliosis, making it much more effective than the usual means of modern medicine. Another very important factor in the choice of azlocillin was the fact that the substance has fewer side effects compared to its analogues.
Due to the fact that one of the most commonthe antibiotics used to treat borreliosis - doxycycline - showed their inability to destroy dangerous microorganisms, a new tool can help fight even the most resistant strains. Another medicine against pathogenic microbes may be cefotaxime, an antibiotic used to treat meningitis, pneumonia, and other respiratory infections. Before releasing improved versions of antibiotics for sale, the authors of the study plan to confirm the results of their experiments in experiments on animals.
Do you know that ticks are more dangerous for women than for men?
Be that as it may, bacteria often adapt andto completely new tools. We have already written about how scientists are trying to cope with such an unpleasant quality for all of humanity in one of our articles on Hi-News.