How ancient fish will help people recover lost limbs

It has long been known that there are on the planetorganisms with tremendous regenerative capabilities, thanks to which they can self-repair even after very serious damage. Unfortunately, you and I have no such bonus. But scientists do not leave attempts to bestow similar qualities to man. And it is quite possible that this will help in this ancient species of pike, which lived to this day in almost unchanged form.

What fish will allow limbs to recover?

According to the publication Phys.The org, scientists at Michigan State University, argue that regeneration of shell pike can open the way to human regeneration. In this case, fish can grow whole fins. More importantly, the researchers focused on how they restore the endochondral bones in their fins, and these parts are in essence equivalent to human arms and legs.

Shell pikes are considered a kind"Dinosaur fish" because of their extreme similarity with their ancient ancestors. - says the author of the work Ingo Braash. They evolve slowly and, because of this, have retained more hereditary elements in their genome than other fish. This means that it will be much easier to find the genes responsible for regeneration.

At the same time, scientists believe that the genes responsiblefor self-healing mechanisms in fish, and in humans. You just need to find the genetic mechanisms that can activate these "sleeping" genes. It is also worth noting that earlier it has been repeatedly suggested that the regenerative abilities of our distant ancestors were much higher than today. So the fact that scientists say there is a certain meaning.

Why precisely fish?

Team of biologists from michigan stateThe university says that from an evolutionary point of view, shell pikes are closer to the last known common ancestor of fish and mammals than other animals. That is, for millions of years, the ability to restore limbs was maintained in a working form in shell pike and other waterfowl. Among the inhabitants of land, the most famous example is the salamander. While during the evolution of terrestrial mammals, their ability to regenerate gradually became weaker.

This is interesting: In Japan, they received permission to cross the embryo of humans and animals.

New research key genes responsiblefor self-restoration in the end, according to scientists, should lead to discoveries in the field of regenerative medicine and the cultivation of lost organs and tissues.

The more we study similarities among mammals and fish, the more we understand that the ancient fish and people from a genetic point of view have a lot in common. - summed up Mr. Braash.

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