Found variations of genes that protect against obesity and diabetes

Obesity and diabetes - verycommon problems, especially in the USA. To improve the lives of people, scientists are constantly looking for drugs to prevent them, and each time they find new ways to influence their sources. For example, researchers from the University of Cambridge discovered variations of the same genes that protect people from obesity and its symptoms — this discovery could lead to the creation of a new type of medicine.

Back in 1998, scientists learned that mutations in the geneMC4R can cause human hereditary obesity — some people are more likely to have fat deposits that increase body weight. Repeated analysis of the same gene in half a million volunteers showed that the gene has 61 variations, some of which, on the contrary, can prevent fat accumulation. Also among them are options to prevent type 2 diabetes and cardiovascular diseases.

New research opened the way to creating newtype of drugs and shed light on the very nature of obesity. According to researcher Sadaf Faruki, their work has once again proved that genetics plays a large role in a person’s physique. Some people are lucky because they have genes that prevent obesity.

A new concept is that genetic variants that protect against diseases can be used as models for the development of more effective and safer drugs.

Luca Lotta, one of the authors of the study

Among the drugs for obesity, there are veryunusual - at the beginning of 2019, researchers at the Massachusetts Institute of Technology presented pills that swell in the stomach. Not only do they suppress the feeling of hunger, so also inside them you can transport medicines and even tiny chambers into the body.

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