While the coronavirus apocalypse is slowly butinevitably becomes a routine, the SARS-CoV-2 virus itself continues to develop. And, unfortunately, he is doing well. According to Futurism.com, citing the South China Morning Post, new studies show that the SARS-CoV-2 virus that causes CoVID-19 could already mutate in more than 30 individual strains. The results hypothetically explain why some cases of CoVID-19 are much more severe than others. A large number of mutations increases the viral load by several hundred times, which leads to a greater spread of viral particles. If you simplify the results as much as possible, then the coronavirus becomes even earlier, and the disease can be more difficult.
Viral load Is a measure of the severity of a viral infection. It is calculated by estimating the amount of viral particles in a certain volume of biological fluid, such as blood or saliva.
April 12, the MedRxiv preprint server hadA study published by Li Lanjuan of Zhejiang University and his colleague is one of China's most prolific virologists. “Sars-CoV-2 has acquired mutations that can significantly alter its pathogenicity,” writes Lee.
Pathogenicity - under favorable conditions, this is a potential opportunity for the microorganism to cause a specific infectious process.
At the time of this writing, the work did not work.peer review and has not been published in a scientific journal (this is a standard procedure for all scientific research). Let me remind you that CoVID-19 attacks the human respiratory system, affecting the lungs and causing SARS. Read more about what coronavirus does with the human body in the material of the editor-in-chief of Hi-News.ru Renat Grishin.
In the course of the study, scientists identified variousstrains also measured in laboratory conditions how quickly and efficiently they can infect and destroy host cells. It turned out that different strains can generate completely different levels of viral load - this means that if one strain generates 270 times more viral load than a less powerful strain, then an infected person produces 270 times more infectious viral particles. This, according to scientists, makes new strains much more dangerous.
It also turned out that the SARS-CoV-2 strain, which spread across Europe and New York, killed far more often than the one that hit other parts of the United States, for example, Washington.
The presence of such mutations significantly complicatesfighting infections and facilitates their spread. It is possible that this may explain the reason why some people are difficult to tolerate the disease, while others do not show any symptoms at all. The results indicate that medical professionals greatly underestimate the overall ability of the virus to mutate. So, Lee and his team found that different strains infect different parts of the world. This means that a vaccine against coronavirus that works for everyone is almost impossible to invent. “The development of drugs and vaccines, although urgent, should take into account the effects of these accumulating mutations in order to avoid potential traps,” the authors of the study write.
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In the course of work, scientists analyzed strains 11randomly selected coronavirus patients from Hangzhou, China, where more than 1264 cases were reported. The researchers then tested how efficiently these strains can infect and kill cells. A sample of 11 people infected with CoVID-19 showed more than 30 different mutations, 19 of which were not previously detected. According to the authors of the article, they obtained evidence that SARS-CoV-2 SARS acquired mutations that could significantly change its pathogenicity.
Scientists were looking for a direct link between mutation andviral pathogenicity. That's because it could be a stepping stone to the invention of the drug. The fact is that they were able to identify the functional characteristics of 11 viral particles, each of which has at least one mutation. By testing samples from 11 infected patients, scientists will learn much more about the virus, as well as our ability to find a cure - since today, finding a cure and vaccine is the ultimate goal for scientists around the world.
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The main thing that they want to convey through their workResearchers, it’s not only to get as deep an understanding of the invention of the vaccine as possible, but also to ensure that healthcare professionals adequately assess the power of the virus. At the time of this writing, more than two million people worldwide have been infected with coronavirus, and the number of deaths has exceeded 186 thousand. Read more about how to distinguish coronavirus from colds and flu and what you need to do to avoid getting sick, read our material, which is updated daily. Be healthy.