Parkinson's disease is one of the mostcommon neurodegenerative diseases. With neurodegenerative diseases in humans, nerve cells die, which leads to the inoperability of various parts of the brain and spinal cord. Symptoms of Parkinson's disease include impaired coordination of movements, tremors at rest, and a general inability to move normally. As a rule, symptoms of the disease appear at the age of 50-60 and intensifies with age... But sometimes signs can occur even before the age of 40. But what exactly causes Parkinson's disease, what is its full symptomatology and can it be cured? Let's figure it out.
- 1 What causes Parkinson's disease?
- 2 Symptoms of Parkinson's disease
- 3 Diagnosis of Parkinson's disease
- 4 Treatment of Parkinson's disease
What causes Parkinson's disease?
The main cause of the diseasedeath of neurons that produce dopamine is considered. This is the name of a biologically active chemical substance that transmits electrochemical impulses between nerve cells. Also, dopamine is a hormone that is responsible for feelings of satisfaction. Lack of dopamine leads to the fact that the gray matter of the brain begins to press on the cerebral cortex. This leads to damage to the parts of the brain that are mainly responsible for the coordination of movements.
There are many causes of Parkinson's disease, each patient has his own. But basically the disease occurs for the following reasons:
- heredity, which becomes the cause in about 20% of cases;
- damage to the meninges with poisonous substances, which happens in case of poisoning and the release of toxins from the liver;
- lack of vitamin D, which plays an important role in building the body's defense mechanisms;
- inflammation caused by bacterial and viral infections such as encephalitis;
- brain injury;
- circulatory disorders in the brain.
First, the person develops the syndromeParkinson's disease, which responds well to treatment. But then the disease flows into the basic form, which is almost impossible to cure. Sometimes Parkinson's disease develops even in 20-year-olds, in which case the cause is usually heredity. Men suffer from the disease more often than women.
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Parkinson's disease symptoms
The clinical picture of Parkinson's disease consists of 4 main symptoms:
- tremor, which consists in the trembling of the human body. At the initial stage, people only have shaking hands and feet, and their fingers move as if a person is counting money. With complications, a person's head, jaw, eyelids and other parts of the body shake. Tremor worse with excitement and disappears during sleep;
- hypokinesia, which consists in the absence of spontaneousmotor activity. That is, a person with Parkinson's disease can sit in one position for hours and not move. Walking character with the presence of small steps, a person has difficulty expressing emotions with the help of facial expressions. Speech becomes monotonous and handwriting is very small;
- muscle rigidity which consists in the fact that the limbs of a person, when flexing and extending, freeze in a given position. People with Parkinson's disease usually slouch with their legs bent slightly at the knee joints;
- postural instability, which consists in the difficulty of starting the movement and the same problems when trying to stop it. It becomes difficult for a person to maintain balance.
It is also worth noting that people with the diseaseParkinson's have metabolic problems. They either lose a lot of weight or gain a lot of weight. They also have increased salivation and sweating. From a psychological point of view, patients are often depressed, behave very sluggishly and tend to repeat the same questions.
Diagnosis of Parkinson's disease
Parkinson's disease manifests itself in old ageand in most cases is irreversible. But if you recognize the disease in the early stages and start timely treatment, the occurrence of negative consequences can be avoided. Usually, the symptoms mentioned above indicate the manifestation of Parkinson's syndrome. But they can also be indicative of other neurodegenerative diseases like Alzheimer's disease. To be sure that it is with Parkinson's disease, doctors refer patients to the so-called magnetic resonance imaging of the brain. If the images of the brain show voids that indicate damage to its parts, then doctors are dealing with Parkinson's disease.
Parkinson's disease treatment
At the moment, Parkinson's disease is consideredincurable. But there are medications and surgery that can reduce the severity of the disease. Basically, medications are aimed at increasing the amount of dopamine in the central nervous system. But dopamine itself is not used in medicines, because from the outside it is poorly perceived by the body. Instead, dopamine precursors are used, which travel to the liver, which produces dopamine.
With regard to surgical operations, the mostthe most modern of them is the stimulation of damaged parts of the brain with the help of electrical discharges. Thin electrodes are inserted into the patient's brain and connected to a small device that remains under the person's skin in the chest area. In most cases, it helps people improve motor coordination and get rid of other symptoms of Parkinson's disease. But this operation is expensive and there is always a risk of equipment breakdown, after which a repeat of the surgical intervention is necessary.
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On our site there are many articles about the diseaseParkinson's because it is one of the most studied diseases in the world. Sometimes doctors manage to save people from many manifestations of the disease, but after that, patients are faced with another problem. What is at stake, you can read in this material from Love Sokovikova.